DOK1 Recombinant Rabbit Monoclonal Antibody (ARC2410) | Invitrogen MA5-37883 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DOK1 Recombinant Rabbit Monoclonal Antibody (ARC2410)

catalog :

MA5-37883

quantity :

100 uL

price :

US 484.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

ARC2410

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

DOK1 Recombinant Rabbit Monoclonal Antibody (ARC2410)

Catalog # :

MA5-37883

Quantity :

100 uL

Price :

US 484.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Western Blot: 1:500-1:1,000

Species :

Human, Mouse, Rat

Clone :

ARC2410

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

DOK1 (P62dok, Docking protein 1) is believed to be a mainly cytoplasmic adaptor protein which down-regulates mitogen-activated protein kinase activation, inhibits cell proliferation and transformation, and promotes cell spreading and cell migration. DOK1 is a major substrate for many tyrosine kinases including c-kit, v-abl, vFPS, EGF, and PDGF. Upon phosphorylation by kinases, DOK1 forms a complex with ras GTPase-activating protein. Phosphorylation on tyrosine residues by the insulin receptor kinase results in the negative regulation of the insulin signaling pathway. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs.

Immunogen :

A synthetic peptide corresponding to a sequence within amino acids 382-481 of human DOK1 (Q99704)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Western Blot: 1:500-1:1,000

Aliases :

AW557123; Docking protein 1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); Dok; DOK 1; DOK1; Dok-1; Downstream of tyrosine kinase 1; downstream of tyrosine kinase-1; MGC117395; MGC138860; p240; p62 dok; p62(dok); p62DOK; pp62; TLP1; TP1; TROVE domain family; TROVE1; VAULT2