IMPA1 Monoclonal Antibody (2177CT172.34.52) | Invitrogen MA5-37791 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IMPA1 Monoclonal Antibody (2177CT172.34.52)

catalog :

MA5-37791

quantity :

200 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2177CT172.34.52

reactivity :

human

application :

western blot

product information

Product Type :

Antibody

Product Name :

IMPA1 Monoclonal Antibody (2177CT172.34.52)

Catalog # :

MA5-37791

Quantity :

200 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Western Blot: 1:1,000-1:2,000

Species :

Human

Clone :

2177CT172.34.52

Isotype :

IgG1, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

IMPA1, also known as Myo-inositol monophosphatase 1, is responsible for the procurement of inositol that is required for synthesis of phosphatidylinositol and polyphosphoinositides. IMPA1 exists as a homodimer and has been identified as the pharmacological target for lithium action in the brain. IMPA1 is the principal enzyme of the phosphatidyl inositol signaling pathway, and inhibition of inositol monophosphatase hydrolysis may underlie the anti-manic and anti-depressant actions of Li+. Studies indicate that a variation in the 277 codon coding region of the IMPA1 gene has not been observed in manic-depressive patients, therefore suggesting that polymorphisms or mutations in the noncoding regions of this gene may influence the lithium response in psychiatric patients.

Immunogen :

recombinant protein from the human region of human IMPA1

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000-1:2,000

Aliases :

2610002K09Rik; 2900059K10Rik; AI325909; D-galactose 1-phosphate phosphatase; IMP; IMP 1; IMPA; IMPA1; Impa1-L; IMPase 1; inositol (myo)-1(or 4)-monophosphatase 1; inositol monophosphatase 1; inositol(myo)-1(or 4)-monophosphatase 1; inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; myo-inositol monophosphatase 1; testicular tissue protein Li 94