USP8 Monoclonal Antibody (460CT35.1.6) | Invitrogen MA5-37573 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

USP8 Monoclonal Antibody (460CT35.1.6)

catalog :

MA5-37573

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

460CT35.1.6

reactivity :

human

application :

western blot

product information

Product Type :

Antibody

Product Name :

USP8 Monoclonal Antibody (460CT35.1.6)

Catalog # :

MA5-37573

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

Western Blot: 1:500-1:4,000

Species :

Human

Clone :

460CT35.1.6

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell energy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structure/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.

Immunogen :

KLH conjugated synthetic peptide between 1-30 amino acids from the C-terminal region of human USP8

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500-1:4,000

Aliases :

AI574262; AW557536; Deubiquitinating enzyme 8; hUBPy; HumORF8; Kiaa0055; mKIAA0055; mUBPy; putative deubiquitinating enzyme; SPG59; Ubiquitin carboxyl-terminal hydrolase 8; ubiquitin isopeptidase Y; ubiquitin specific peptidase 8; ubiquitin specific protease 8; ubiquitin thioesterase 8; ubiquitin thiolesterase 8; ubiquitin-specific-processing protease 8; Ubpy; USP8