SPRED1 Monoclonal Antibody (462CT2.5.1) | Invitrogen MA5-37564 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SPRED1 Monoclonal Antibody (462CT2.5.1)

catalog :

MA5-37564

quantity :

400 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

462CT2.5.1

The same clone is also sold as:

Santa Cruz Biotechnology: sc-517362

reactivity :

human, mouse

application :

western blot

product information

Product Type :

Antibody

Product Name :

SPRED1 Monoclonal Antibody (462CT2.5.1)

Catalog # :

MA5-37564

Quantity :

400 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Western Blot: 1:100-1:250

Species :

Human, Mouse

Clone :

462CT2.5.1

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The Ras-MAP kinase pathway is essential for the differentiation of neuronal cells and myocytes; it is inhibited by Spred1, a member of the Sprouty family of proteins. Spred1 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).

Immunogen :

purified His-tagged SPRED1 protein (fragment)

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:100-1:250

Aliases :

5730461F13Rik; AL024345; AW047647; hSpred1; NFLS; PPP1R147; protein phosphatase 1, regulatory subunit 147; SPRED1; spred-1; sprouty protein with EVH-1 domain 1, related sequence; sprouty related EVH1 domain containing 1; sprouty related, EVH1 domain containing 1; sprouty-related protein 1 with EVH-1 domain; sprouty-related, EVH1 domain containing 1; sprouty-related, EVH1 domain-containing protein 1; suppressor of Ras/MAPK activation