SWAP70 Monoclonal Antibody (434CT16.5.5) | Invitrogen MA5-37562 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SWAP70 Monoclonal Antibody (434CT16.5.5)

catalog :

MA5-37562

quantity :

400 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

434CT16.5.5

reactivity :

human

application :

western blot

product information

Product Type :

Antibody

Product Name :

SWAP70 Monoclonal Antibody (434CT16.5.5)

Catalog # :

MA5-37562

Quantity :

400 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Western Blot: 1:100-1:1,000

Species :

Human

Clone :

434CT16.5.5

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

SWAP70 is a 585 amino acid regulatory protein belonging to the pleckstrin-like family with a PH domain essential for phosphatidylinositol 3, 4, 5-trisphosphate binding. SWAP70 acts as a link between the recognition of specific switch regions and causation of a DNA break and is involved in both nuclear events and in signaling B-cell activation. As a guanine nucleotide exchange factor (GEF) it transduces signals from tyrosine kinase receptors to RAC, independent of RAS. As a multiple functional signaling protein, and a component of SWAP enzyme complex, it mediates signaling of membrane ruffling by tyrosine kinase growth factor receptors, actin cytoskeleton and cell protrusion. It is widely expressed in most tissues, mature B-cells, including those associated with mucosa-associated tissue and bronchus-associated tissue, monocytes and macrophages.

Immunogen :

purified His-tagged SWAP70 protein (fragment)

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:100-1:1,000

Aliases :

70kDa; AV235546; FLJ39540; HSPC321; Kiaa0640; KIAA0640 protein; SWA-70 protein; SWAP complex protein; SWAP complex protein, 70 kDa; SWAP switching B-cell complex 70; SWAP switching B-cell complex 70kDa subunit; SWAP70; SWAP-70; SWAP-70 protein; Switch-associated protein 70