CNOT4 Monoclonal Antibody (343CT14.6.5) | Invitrogen MA5-37532 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CNOT4 Monoclonal Antibody (343CT14.6.5)

catalog :

MA5-37532

quantity :

400 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

343CT14.6.5

The same clone is also sold as:

Santa Cruz Biotechnology: sc-517324

reactivity :

human, mouse

application :

western blot

product information

Product Type :

Antibody

Product Name :

CNOT4 Monoclonal Antibody (343CT14.6.5)

Catalog # :

MA5-37532

Quantity :

400 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Western Blot: 1:8,000

Species :

Human, Mouse

Clone :

343CT14.6.5

Isotype :

IgG2a, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CNOT4 is a 575 amino acid protein with E3 ubiquitin ligase activity, mainly involved in protein modification and protein ubiquitination. It contains a ring type zinc finger domain of the C4C4 type, an RNA recognition motif and a bipartite nuclear localization signal.Studies show that CNOT4 is a component of the CCR4-NOT (CAF1) core complex that functions as general transcription regulation complex and has both a positive as well as a negative effect on the transcription of multiple functionally unrelated genes, thus controls gene expression. CNOT4 interacts with CNOT1 via C-terminus and with E2 ubiquitin ligases via C4C4 RING domain. Reports suggest that CNOT4 gets phosphorylated in response to DNA damage on consensus sites recognized by ATM and ATR.

Immunogen :

CNOT4 recombinant protein

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:8,000

Aliases :

CCR4-associated factor 4; CCR4-NOT transcription complex subunit 4; CCR4-NOT transcription complex subunit 4 L homeolog; CCR4-NOT transcription complex subunit 4 S homeolog; CCR4-NOT transcription complex subunit 4 S homeolog; CCR4-NOT transcription complex, subunit 4; CCR4-NOT transcription complex, subunit 4 isoform a; CLONE243; cnot4; cnot4.S; E3 ubiquitin-protein ligase CNOT4; hypothetical protein; negative regulator of transcription 4; Not4; NOT4 (negative regulator of transcription 4, yeast) homolog; Not4h; Not4hp; Potential transcriptional repressor NOT4Hp; RING-type E3 ubiquitin transferase CNOT4; transcriptional repressor NOT4Hp; XELAEV_18019807mg