This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Phospho-Ask1 (Thr838) Recombinant Rabbit Monoclonal Antibody (Ask1T838-8D12)
catalog :
MA5-37433
quantity :
20 uL
price :
US 329.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
Ask1T838-8D12

The same clone is also sold as:
reactivity :
human, mouse
application :
flow cytometry
product information
Product Type :
Antibody
Product Name :
Phospho-Ask1 (Thr838) Recombinant Rabbit Monoclonal Antibody (Ask1T838-8D12)
Catalog # :
MA5-37433
Quantity :
20 uL
Price :
US 329.00
Clonality :
Recombinant Monoclonal
Purity :
Protein A/G
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: 1-1,000 ng/mL
Species :
Human, Mouse
Clone :
Ask1T838-8D12
Isotype :
IgG, kappa
Storage :
-20 C
Description :
MAP3K5 (ASK1) is a serine/threonine kinase that is abundantly expressed in human heart and pancreas and are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses. A novel MAP kinase kinase kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5. ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively. ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx. Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apoptosis. ASK1 is expressed in variety of human and mouse tissues.
Immunogen :
A synthetic phospho-peptide corresponding to residues surrounding Thr838 of human phospho Ask1.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1-1,000 ng/mL
Aliases :
7420452D20Rik; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK; ASK 1; ASK1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP/ERK kinase kinase 5; Map3k5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; RGD1306565; RP3-325F22.4
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA