Phospho-c-Cbl (Tyr774) Recombinant Rabbit Monoclonal Antibody (CblY774-R3B8)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-c-Cbl (Tyr774) Recombinant Rabbit Monoclonal Antibody (CblY774-R3B8)

catalog :

MA5-37347

quantity :

20 uL

price :

US 329.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

CblY774-R3B8

The same clone is also sold as:

Abcam: ab278760, ab278602, ab278603

reactivity :

human, mouse

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

Phospho-c-Cbl (Tyr774) Recombinant Rabbit Monoclonal Antibody (CblY774-R3B8)

Catalog # :

MA5-37347

Quantity :

20 uL

Price :

US 329.00

Clonality :

Recombinant Monoclonal

Purity :

Protein A/G

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1-1,000 ng/mL

Species :

Human, Mouse

Clone :

CblY774-R3B8

Isotype :

IgG, kappa

Storage :

-20 C

Description :

Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling.

Immunogen :

A synthetic phospho-peptide corresponding to residues surrounding Tyr774 of human phospho c-Cbl.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1-1,000 ng/mL

Aliases :

4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL