Phospho-Chk2 (Thr68) Recombinant Rabbit Monoclonal Antibody (Chk2T68-D12), PE

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-Chk2 (Thr68) Recombinant Rabbit Monoclonal Antibody (Chk2T68-D12), PE

catalog :

MA5-37268

quantity :

10 Tests

price :

US 197.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

clone name :

Chk2T68-D12

The same clone is also sold as:

Abcam: ab278548, ab278651, ab278738, ab278577

reactivity :

human, mouse

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

Phospho-Chk2 (Thr68) Recombinant Rabbit Monoclonal Antibody (Chk2T68-D12), PE

Catalog # :

MA5-37268

Quantity :

10 Tests

Price :

US 197.00

Clonality :

Recombinant Monoclonal

Purity :

Protein A/G

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 5 uL/1x10^6 cells

Species :

Human, Mouse

Clone :

Chk2T68-D12

Isotype :

IgG, kappa

Storage :

4 C

Description :

CHEK2 (CHK2) is a serine/threonine kinase and a component of the DNA damage checkpoint pathway. A mutation in CHK2 has been linked to cancer. CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins. In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage. Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53. Also, mutations in CHK2 are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

Immunogen :

A synthetic phosphorus-peptide corresponding to residues surrounding Thr68 of human Chk2 .

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL/1x10^6 cells

Aliases :

CDS1; cds1 homolog; Checkpoint kinase 2; Checkpoint like protein CHK2; checkpoint-like protein CHK2; Chek2; Chk2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; CHK2 checkpoint homolog (S. pombe); Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; HuCds 1; HuCds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; Rad53; Rad53 homolog; RP11-436C9.1; Serine/threonine protein kinase Chk2; serine/threonine-protein kinase Chk2