This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Phospho-PDPK1 (Ser241) Recombinant Rabbit Monoclonal Antibody (PDK1S241-F7), PE
catalog :
MA5-37089
quantity :
100 Tests
price :
US 484.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
PE
clone name :
PDK1S241-F7

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
product information
Product Type :
Antibody
Product Name :
Phospho-PDPK1 (Ser241) Recombinant Rabbit Monoclonal Antibody (PDK1S241-F7), PE
Catalog # :
MA5-37089
Quantity :
100 Tests
Price :
US 484.00
Clonality :
Recombinant Monoclonal
Purity :
Protein A/G
Host :
Rabbit
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL/1x10^6 cells
Species :
Human
Clone :
PDK1S241-F7
Isotype :
IgG, kappa
Storage :
4 C
Description :
PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDPK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase, and the stimulation of glycogen synthesis. Because of the role that PDPK1 plays in insulin-induced glycogen synthesis and PKC activation, it is a potentially important target for metabolic drug research.
Immunogen :
A synthetic phospho-peptide corresponding to residues surrounding Ser241 of human phospho PDPK1.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL/1x10^6 cells
Aliases :
3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; HGNC:8809; hPDK1; isoenzyme 1; kinase isoenzyme 1; lipoamide; mPDK1; OTTHUMP00000174525; OTTHUMP00000205076; PDK1; PDPK1; PDPK2; PDPK2P; Pkb kinase; PkB kinase like gene 1; PkB-like 1; PRO0461; Protein kinase B kinase
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA