MFN1 Monoclonal Antibody (3H3) | Invitrogen MA5-36240 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MFN1 Monoclonal Antibody (3H3)

catalog :

MA5-36240

quantity :

100 ug

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3H3

reactivity :

human

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

MFN1 Monoclonal Antibody (3H3)

Catalog # :

MA5-36240

Quantity :

100 ug

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 2 ug/mL, Western Blot: 0.1-0.5 ug/mL

Species :

Human

Clone :

3H3

Isotype :

IgG2b

Storage :

-20 C

Description :

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminal of human Mitofusin 1 (23-49aa DQLLEFVTEGSHFVEATYKNPELDRIA).

Format :

Lyophilized

Applications w/Dilutions :

Immunocytochemistry: 2 ug/mL, Western Blot: 0.1-0.5 ug/mL

Aliases :

2310002F04Rik; 6330416C07Rik; D3Ertd265e; DKFZp762F247; EC 3.6.5; FLJ20693; Fzo homolog; Fzo1b; hfzo1; hfzo2; HR2; Mfn1; MFN2; MGC41806; mitochondrial mitofusin 1; mitochondrial transmembrane GTPase Fzo-1; mitochondrial transmembrane GTPase FZO1B; mitochondrial transmembrane GTPase FZO-2; mitofusin 1; mitofusin 2; mitofusin-1; mKIAA4032; putative transmembrane GTPase; transmembrane GTPase MFN1