DOK1 Recombinant Rabbit Monoclonal Antibody (JE54-52) | Invitrogen MA5-36191 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DOK1 Recombinant Rabbit Monoclonal Antibody (JE54-52)

catalog :

MA5-36191

quantity :

100 uL

price :

US 474.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

JE54-52

reactivity :

human, rat

application :

western blot

product information

Product Type :

Antibody

Product Name :

DOK1 Recombinant Rabbit Monoclonal Antibody (JE54-52)

Catalog # :

MA5-36191

Quantity :

100 uL

Price :

US 474.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Rat

Applications :

Western Blot: 1:500-1:2,000

Species :

Human, Rat

Clone :

JE54-52

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

DOK1 (P62dok, Docking protein 1) is believed to be a mainly cytoplasmic adaptor protein which down-regulates mitogen-activated protein kinase activation, inhibits cell proliferation and transformation, and promotes cell spreading and cell migration. DOK1 is a major substrate for many tyrosine kinases including c-kit, v-abl, vFPS, EGF, and PDGF. Upon phosphorylation by kinases, DOK1 forms a complex with ras GTPase-activating protein. Phosphorylation on tyrosine residues by the insulin receptor kinase results in the negative regulation of the insulin signaling pathway. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs.

Immunogen :

Recombinant protein within Human DOK1 aa 360-481

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500-1:2,000

Aliases :

AW557123; Docking protein 1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); Dok; DOK 1; DOK1; Dok-1; Downstream of tyrosine kinase 1; downstream of tyrosine kinase-1; MGC117395; MGC138860; p240; p62 dok; p62(dok); p62DOK; pp62; TLP1; TP1; TROVE domain family; TROVE1; VAULT2