LYRIC Monoclonal Antibody (C6-C10) | Invitrogen MA5-36100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LYRIC Monoclonal Antibody (C6-C10)

catalog :

MA5-36100

quantity :

100 uL

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

C6-C10

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

LYRIC Monoclonal Antibody (C6-C10)

Catalog # :

MA5-36100

Quantity :

100 uL

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat

Clone :

C6-C10

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Metadherin (Metastasis adhesion protein), also known as MTDH, LYsine-RIch CEACAM1 co-isolated (LYRIC), is a novel protein that localizes with the tight junction proteins ZO-1 and occludin in polarized epithelial cells. At the tight junction, it acts not as a structural component, but is rather recruited during the maturation of the tight junction complex. Metadherin is overexpressed in breast cancer tissue and breast tumor xenografts, while much lower levels are expressed in normal breast tissue. Metadherin binds to lung vasculature, one of the four common sites of breast cancer metastasis, through a C-terminal segment in the extracellular domain; blocking this lung-homing domain with antibodies or inhibiting metadherin with siRNA has been reported to inhibit breast cancer metastasis.

Immunogen :

Recombinant protein within Human LYRIC aa 6-233

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

2610103J23Rik; 3D3; 3D3/Lyric; AEG1; AEG-1; astrocyte elevated gene 1; astrocyte elevated gene-1 protein; AV353288; D8Bwg1112e; LYRIC; LYRIC/ MTDH; LYRIC/3D3; lysine-rich CEACAM1 co-isolated protein; Metadherin; metastasis adhesion protein; MTDH; Protein LYRIC