ACE2 Recombinant Rabbit Monoclonal Antibody (5X5W10) | Invitrogen MA5-36088 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ACE2 Recombinant Rabbit Monoclonal Antibody (5X5W10)

catalog :

MA5-36088

quantity :

100 uL

price :

US 434.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

5X5W10

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

ACE2 Recombinant Rabbit Monoclonal Antibody (5X5W10)

Catalog # :

MA5-36088

Quantity :

100 uL

Price :

US 434.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1 ug/mL, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:2,000, Western Blot: 1:100-1:500

Species :

Human, Mouse, Rat

Clone :

5X5W10

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 18-740 of human ACE2 (NP_0685761)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:2,000, Western Blot: 1:100-1:500

Aliases :

2010305L05Rik; ACE 2; Ace2; ACEH; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin I converting enzyme 2; angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog; anigotensin I converting enzyme 2; anigotensin-converting enzyme-related carboxypeptidase; metalloprotease MPROT15; peptidyl-dipeptidase A; Processed angiotensin-converting enzyme 2; renal angiotensin-converting enzyme 2; UNQ868/PRO1885