CRALBP Recombinant Rabbit Monoclonal Antibody (ARC1502) | Invitrogen MA5-35791 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CRALBP Recombinant Rabbit Monoclonal Antibody (ARC1502)

catalog :

MA5-35791

quantity :

100 uL

price :

US 474.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

ARC1502

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

CRALBP Recombinant Rabbit Monoclonal Antibody (ARC1502)

Catalog # :

MA5-35791

Quantity :

100 uL

Price :

US 474.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1 ug/mL, Immunocytochemistry: 1:200-1:2,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:1,000-1:6,000

Species :

Human, Mouse, Rat

Clone :

ARC1502

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Cellular retinaldehyde-binding protein (CRALBP) plays an important role in the regeneration of 11-cis-retinal for use in rod visual pigments such as opsin and rhodopsin. Once 11-cis-retinal is photoisomerized in the rod outer segment, it is converted to all-trans-retinal and further modified into all-trans-retinol. All-trans-retinol then diffuses into the retinal pigment epithelium (RPE) to be converted back to 11-cis-retinol and further oxidized into 11-cis-retinal (both by CRALBP). Genetic mutations involving CRALBP's lack of function have been linked to visual disease such as bothnia dystrophy, retinitis punctata albescens, retina pigmentosa, and Newfoundland rod-cone dystrophy. The presence of CRALBP serves as a marker for RPE and Muller glial cells of the retina.

Immunogen :

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CRALBP (P12271)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunocytochemistry: 1:200-1:2,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:1,000-1:6,000

Aliases :

3110056M11Rik; cellular retinaldehyde-binding protein; cellular retinaldehyde-binding protein-1; CRALBP; retinaldehyde binding protein 1; retinaldehyde-binding protein 1; retinaldehyde-binding protein precursor; Rlbp1