CBX4 Recombinant Rabbit Monoclonal Antibody (ARC1201) | Invitrogen MA5-35645 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CBX4 Recombinant Rabbit Monoclonal Antibody (ARC1201)

catalog :

MA5-35645

quantity :

100 uL

price :

US 474.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

ARC1201

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

CBX4 Recombinant Rabbit Monoclonal Antibody (ARC1201)

Catalog # :

MA5-35645

Quantity :

100 uL

Price :

US 474.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1 ug/mL, Immunoprecipitation: 0.5 ug-4 ug antibody for 200 ug-400 ug extracts of, Western Blot: 1:500-1:1,000

Species :

Human, Mouse, Rat

Clone :

ARC1201

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.

Immunogen :

A synthetic peptide corresponding to amino acids 461-560 of human CBX4.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunoprecipitation: 0.5 ug-4 ug antibody for 200 ug-400 ug extracts of, Western Blot: 1:500-1:1,000

Aliases :

Cbx4; chromobox 4; chromobox homolog 4; chromobox homolog 4 (Pc class homolog, Drosophila); chromobox protein homolog 4; chromobox-like protein 4; E3 SUMO-protein ligase CBX4; E3 SUMO-protein transferase CBX4; hPc2; MPc2; NBP16; NS5ATP1-binding protein 16; Pc class 2 homolog; PC2; Polycomb 2 homolog