GATA2/GATA3 Recombinant Rabbit Monoclonal Antibody (ARC1209) | Invitrogen MA5-35637 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GATA2/GATA3 Recombinant Rabbit Monoclonal Antibody (ARC1209)

catalog :

MA5-35637

quantity :

100 uL

price :

US 474.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

ARC1209

reactivity :

human, mouse, rat

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

GATA2/GATA3 Recombinant Rabbit Monoclonal Antibody (ARC1209)

Catalog # :

MA5-35637

Quantity :

100 uL

Price :

US 474.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1 ug/mL, Western Blot: 1:500-1:1,000

Species :

Human, Mouse, Rat

Clone :

ARC1209

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human GATA2/3 (NP_1160272)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:500-1:1,000

Aliases :

DCML; EMBL:AAK51128.1}; endothelial transcription factor GATA-2; GATA binding protein 2; GATA binding protein 3; Gata2; Gata-2; gata2 {ECO:0000312; Gata3; Gata-3; GATA-binding factor 3; GATA-binding protein 2; GATA-binding protein 3; GATA-bindning protein 2; HDR; HDRS; IMD21; jal; MGC2346; MGC5199; MGC5445; MONOMAC; NFE1B; trans-acting T-cell-specific transcription factor GATA-3