GRB2 Recombinant Rabbit Monoclonal Antibody (ARC0430) | Invitrogen MA5-35238 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GRB2 Recombinant Rabbit Monoclonal Antibody (ARC0430)

catalog :

MA5-35238

quantity :

100 uL

price :

US 474.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

ARC0430

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

GRB2 Recombinant Rabbit Monoclonal Antibody (ARC0430)

Catalog # :

MA5-35238

Quantity :

100 uL

Price :

US 474.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1 ug/mL, Immunocytochemistry: 1:100-1:800, Immunohistochemistry (Paraffin): 1:200-1:800, Immunoprecipitation: 0.5 ug-4 ug antibody for 200 ug-400 ug extracts of, Western Blot: 1:1,000-1:6,000

Species :

Human, Mouse, Rat

Clone :

ARC0430

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.

Immunogen :

A synthetic peptide corresponding to a sequence within amino acids 118-217 of human GRB2 (P62993)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunocytochemistry: 1:100-1:800, Immunohistochemistry (Paraffin): 1:200-1:800, Immunoprecipitation: 0.5 ug-4 ug antibody for 200 ug-400 ug extracts of, Western Blot: 1:1,000-1:6,000

Aliases :

AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg