SATB2 Monoclonal Antibody (CL0320) | Invitrogen MA5-34976 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SATB2 Monoclonal Antibody (CL0320)

catalog :

MA5-34976

quantity :

100 uL

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CL0320

The same clone is also sold as:

Novus Biologicals: NBP2-52914

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

SATB2 Monoclonal Antibody (CL0320)

Catalog # :

MA5-34976

Quantity :

100 uL

Price :

US 484.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Immunocytochemistry: 2-10 ug/mL, Immunohistochemistry (Paraffin): 1:500-1:1,000, Western Blot: 1 ug/mL

Species :

Human, Rat

Clone :

CL0320

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

DNA-binding protein SATB2 binds to DNA at the nuclear matrix- or scaffold associated regions. It is thought to recognize the sugar-phosphate structure of double-stranded DNA. SATB2 is a transcription factor controlling nuclear gene expression by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. It also acts as a docking site for several chromatin remodeling enzymes by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. SATB2 is required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes - probably by modulating BCL11B expression. It is a repressor of Ctip2 and a regulatory determinant of corticocortical connections in the developing cerebral cortex. Mutations in the gene are associate with cleft palate isolated (CPI).

Immunogen :

Recombinant Protein corresonding to Human SATB2

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2-10 ug/mL, Immunohistochemistry (Paraffin): 1:500-1:1,000, Western Blot: 1 ug/mL

Aliases :

DNA-binding protein SATB2; FLJ21474; FLJ32076; GLSS; KIAA1034; KIAA1034-like DNA binding protein; MGC119474; MGC119477; mKIAA1034; RGD1562369; SATB family member 2; SATB homeobox 2; SATB2; special AT-rich sequence binding protein 2; special AT-rich sequence-binding protein 2; two cut domains-containing homeodomain protein