This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Zika Virus Envelope Protein Monoclonal Antibody (6932)
catalog :
MA5-33303
quantity :
1 mL
price :
US 484.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6932
application :
western blot, ELISA, immunocytochemistry
product information
Product Type :
Antibody
Product Name :
Zika Virus Envelope Protein Monoclonal Antibody (6932)
Catalog # :
MA5-33303
Quantity :
1 mL
Price :
US 484.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Virus
Applications :
ELISA: 1:20-1:200, Immunocytochemistry: 1:10-1:50, Western Blot: Assay-dependent
Species :
Virus
Clone :
6932
Isotype :
IgG2b
Storage :
4 C
Description :
As a member of the Flaviviridae family, ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-transitionally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5)(1). The glycosated NS1 forms a homodimer inside the cells and is necessary for viral replication and late in infection (2). NS1 is also secreted into the extracellular space as a hexameric lipoprotein particle, which assists the virus in immune evasion and pathogenesis by interacting with components from both innate and adaptive immune systems as well as other host factors (1). Reference 1) Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F. (2016). Nat. Struct. Mol. Biol. 23, 456-458. 2) Suthar, M.S., Diamond, M.S. and Gale, M. Jr. (2013). Nat. Rev. Microbiol. 11, 115-128.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:20-1:200, Immunocytochemistry: 1:10-1:50, Western Blot: Assay-dependent
Aliases :
Zika Envelope
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA