Phospho-GATA3 (Ser308) Recombinant Rabbit Monoclonal Antibody (1E5)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-GATA3 (Ser308) Recombinant Rabbit Monoclonal Antibody (1E5)

catalog :

MA5-33141

quantity :

100 uL

price :

US 491.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

1.00E+05

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

Phospho-GATA3 (Ser308) Recombinant Rabbit Monoclonal Antibody (1E5)

Catalog # :

MA5-33141

Quantity :

100 uL

Price :

US 491.00

Clonality :

Recombinant Monoclonal

Purity :

Antigen affinity chromatography, Protein G

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:5,000

Species :

Human

Clone :

1.00E+05

Isotype :

IgG

Storage :

-20 C or -80 C if preferred

Description :

The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.

Immunogen :

A synthesized peptide derived from human Phospho-GATA3 (S308)

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:5,000

Aliases :

EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3