This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MMP12 Recombinant Rabbit Monoclonal Antibody (RM381)
catalog :
MA5-33072
quantity :
100 uL
price :
US 474.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
RM381

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
MMP12 Recombinant Rabbit Monoclonal Antibody (RM381)
Catalog # :
MA5-33072
Quantity :
100 uL
Price :
US 474.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1:1,000-1:2,500, Western Blot: 1:200-1:1,000
Species :
Human
Clone :
RM381
Isotype :
IgG
Storage :
-20 C
Description :
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
Immunogen :
A peptide corresponding to the C-terminus of human Matrix metalloproteinase-12 (MMP-12).
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:1,000-1:2,500, Western Blot: 1:200-1:1,000
Aliases :
3.4.24.65; AV378681; HME; Macrophage elastase; macrophage metalloelastase; macrophage-metalloelastase; matrix metallo protease; matrix metallopeptidase 12; matrix metallopeptidase 12 (macrophage elastase); matrix metalloproteinase 12; matrix metalloproteinase 12 (macrophage elastase); matrix metalloproteinase-12; ME; MGC138506; MME; Mmel; MMP; Mmp12; MMP-12; MMPs
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA