This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Acetylated Lysine Recombinant Rabbit Monoclonal Antibody (RM101)
catalog :
MA5-33031
quantity :
100 ug
price :
US 480.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
RM101
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
product information
Product Type :
Antibody
Product Name :
Acetylated Lysine Recombinant Rabbit Monoclonal Antibody (RM101)
Catalog # :
MA5-33031
Quantity :
100 ug
Price :
US 480.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Chemical
Applications :
ChIP Assay: 1:100-1:500, Immunocytochemistry: 1:100-1:500, Immunohistochemistry: 1:100-1:500, Immunoprecipitation: 1:100-1:500, Luminex: Assay-dependent, Western Blot: 1:500-1:2,000
Species :
Chemical
Clone :
RM101
Isotype :
IgG
Storage :
-20 C
Description :
In the nucleus, DNA is tightly packed into nucleosomes generating an environment which is highly repressive towards DNA processes such as transcription. Acetylation of lysine residues within proteins has emerged as an important mechanism used by cells to overcome this repression. The acetylation of non-histone proteins such as transcription factors, as well as histones appears to be involved in this process. Acetylation may result in structural transitions as well as specific signaling within discrete chromatin domains. The role of acetylation in intracellular signaling has been inferred from the binding of acetylated peptides by the conserved bromodomain. Furthermore, recent findings suggest that bromodomain/acetylated-lysine recognition can serve as a regulatory mechanism in protein-protein interactions in numerous cellular processes such as chromatin remodeling and transcriptional activation.
Immunogen :
Acetyllysine-BSA.
Format :
Liquid
Applications w/Dilutions :
ChIP Assay: 1:100-1:500, Immunocytochemistry: 1:100-1:500, Immunohistochemistry: 1:100-1:500, Immunoprecipitation: 1:100-1:500, Luminex: Assay-dependent, Western Blot: 1:500-1:2,000
Aliases :
Acetyl Lysine; Acetylated Lysine; Acetyllysine
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA