AMPK beta-1 Monoclonal Antibody (1A7) | Invitrogen MA5-32975 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

AMPK beta-1 Monoclonal Antibody (1A7)

catalog :

MA5-32975

quantity :

100 uL

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1A7

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

AMPK beta-1 Monoclonal Antibody (1A7)

Catalog # :

MA5-32975

Quantity :

100 uL

Price :

US 480.00

Clonality :

Monoclonal

Purity :

Antigen affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:800, Immunoprecipitation: 1:50-1:200, Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Clone :

1A7

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

AMPK beta 1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

Immunogen :

Purified recombinant human AMPKbeta1 protein fragments expressed in E.coli.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:800, Immunoprecipitation: 1:50-1:200, Western Blot: 1:1,000

Aliases :

1300015D22Rik; 5'-AMP-activated protein kinase 40 kDa subunit; 5-AMP-activated protein kinase beta subunit; 5'-AMP-activated protein kinase beta-1 subunit; 5'-AMP-activated protein kinase subunit beta-1; 5'-AMP-activated protein kinase subunit beta-1-like protein; 5'-AMP-activated protein kinase, beta subunit; AAKB1; AMP-activated protein kinase beta subunit; AMPK; AMPK beta 1; AMPK beta -1 chain; AMPK beta-1 chain; AMPK subunit beta-1; AMPKb; AMPK-beta1; AU021155; E430008F22; HAMPKb; kinase AMPK-beta1; kinase pAMPK; pAMPK; Prkab1; protein kinase AMP-activated non-catalytic subunit beta 1; protein kinase, AMP-activated, beta 1 non-catalytic subunit; protein kinase, AMP-activated, noncatalytic, beta-1