HK2 Monoclonal Antibody (7E7) | Invitrogen MA5-32952 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HK2 Monoclonal Antibody (7E7)

catalog :

MA5-32952

quantity :

100 uL

price :

US 491.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7.00E+07

reactivity :

human, rat

application :

western blot, flow cytometry

citations: 2

Reference
Lan Z, Sun F, Chen C, Niu L, Shi J, Zhang W. CircPRDM5 inhibits the proliferation, migration, invasion, and glucose metabolism of gastric cancer cells by reducing GCNT4 expression in a miR-485-3p-dependent manner. Kaohsiung J Med Sci. 2024;40:231-243 pubmed publisher
Ni J, Xi X, Xiao S, Xiao X. Silencing of circHIPK3 Sensitizes Paclitaxel-Resistant Breast Cancer Cells to Chemotherapy by Regulating HK2 Through Targeting miR-1286. Cancer Manag Res. 2021;13:5573-5585 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HK2 Monoclonal Antibody (7E7)

Catalog # :

MA5-32952

Quantity :

100 uL

Price :

US 491.00

Clonality :

Monoclonal

Purity :

Antigen affinity chromatography

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Flow Cytometry: 1:50-1:100, Western Blot: 1:1,000

Species :

Human, Rat

Clone :

7.00E+07

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Immunogen :

Synthetic peptide, corresponding to amino acids N-terminus of Human Hexokinase-2.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:100, Western Blot: 1:1,000

Aliases :

AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738