PCSK9 Monoclonal Antibody (2F1) | Invitrogen MA5-32843 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PCSK9 Monoclonal Antibody (2F1)

catalog :

MA5-32843

quantity :

100 uL

price :

US 470.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2F1

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 4

Reference
Ilahibaks N, Kluiver T, de Jong O, de Jager S, Schiffelers R, Vader P, et al. Extracellular vesicle-mediated delivery of CRISPR/Cas9 ribonucleoprotein complex targeting proprotein convertase subtilisin-kexin type 9 (Pcsk9) in primary mouse hepatocytes. J Extracell Vesicles. 2024;13:e12389 pubmed publisher
Buldak L, Machnik G, Skudrzyk E, Boldys A, Maliglowka M, Kosowski M, et al. Exenatide prevents statin-related LDL receptor increase and improves insulin secretion in pancreatic beta cells (1.1E7) in a protein kinase A-dependent manner. J Appl Biomed. 2022;20:130-140 pubmed publisher
Merleev A, Ji Xu A, Toussi A, Tsoi L, Le S, Luxardi G, et al. Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G. JCI Insight. 2022;7: pubmed publisher
Suh J, Son Y, Yoo J, Goh Y, Seidah N, Lee S, et al. Proprotein convertase subtilisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cells. Neoplasia. 2021;23:993-1001 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PCSK9 Monoclonal Antibody (2F1)

Catalog # :

MA5-32843

Quantity :

100 uL

Price :

US 470.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1:50-1:200, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1,000

Species :

Human, Mouse

Clone :

2F1

Isotype :

IgG2b

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

Immunogen :

Recombinant protein with Human PCSK9 1-201

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:200, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1,000

Aliases :

AI415265; AI747682; convertase subtilisin; convertase subtilisin/kexin type 9 preproprotein; FH3; HCHOLA3; hypercholesterolemia; LDLCQ1; NARC1; NARC-1; neural apoptosis regulated convertase 1; neural apoptosis-regulated convertase 1; OTTHUMP00000009833; PC9; PCSK9; Proprotein convertase 9; proprotein convertase PC9; proprotein convertase subtilisin/kexin type 9; PSEC0052; Subtilisin/kexin-like protease PC9