LOX Recombinant Rabbit Monoclonal Antibody (JU30-23) | Invitrogen MA5-32817 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LOX Recombinant Rabbit Monoclonal Antibody (JU30-23)

catalog :

MA5-32817

quantity :

100 uL

price :

US 474.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

JU30-23

reactivity :

human, mouse, rat, zebrafish

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Horton E, Vallmajo Martin Q, Martin I, Snedeker J, Ehrbar M, Blache U. Extracellular Matrix Production by Mesenchymal Stromal Cells in Hydrogels Facilitates Cell Spreading and Is Inhibited by FGF-2. Adv Healthc Mater. 2020;9:e1901669 pubmed publisher

product information

Product Type :

Antibody

Product Name :

LOX Recombinant Rabbit Monoclonal Antibody (JU30-23)

Catalog # :

MA5-32817

Quantity :

100 uL

Price :

US 474.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat, Zebrafish

Applications :

Flow Cytometry: 1:1000, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:200-1:1000, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat, Zebrafish

Clone :

JU30-23

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.

Immunogen :

Synthetic peptide within Human LOX aa 368-417

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:1000, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:200-1:1000, Western Blot: 1:500-1:2,000

Aliases :

AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160