GCLM Recombinant Rabbit Monoclonal Antibody (JM39-61) | Invitrogen MA5-32783 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GCLM Recombinant Rabbit Monoclonal Antibody (JM39-61)

catalog :

MA5-32783

quantity :

100 uL

price :

US 464.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

JM39-61

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 1

Reference
Lei Y, Guerra Martinez C, Torres Odio S, Bell S, Birdwell C, Bryant J, et al. Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice. Sci Adv. 2021;7: pubmed publisher

product information

Product Type :

Antibody

Product Name :

GCLM Recombinant Rabbit Monoclonal Antibody (JM39-61)

Catalog # :

MA5-32783

Quantity :

100 uL

Price :

US 464.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:50-1:100, Immunohistochemistry (Frozen): 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:1,000-1:2,000

Species :

Human, Mouse, Rat

Clone :

JM39-61

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Gamma-glutamylcysteine synthetase (gamma-GCS) is the rate limiting enzyme for glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. Gamma-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic ntioxidants, heat shock, oxidants and cytokines.

Immunogen :

Recombinant protein within Human GCLM aa 225-274

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:100, Immunohistochemistry (Frozen): 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:1,000-1:2,000

Aliases :

AI649393; gamma glutamylcysteine synthetase; gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Gclm; Gcmc; GCS light chain; Glclr; glutamate cysteine ligase (gamma-glutamylcysteine synthetase), regulatory; glutamate cysteine ligase, modifier subunit; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD); glutamate-cysteine ligase modifier subunit; glutamate--cysteine ligase modifier subunit; glutamate-cysteine ligase modifier subunit delta2 alternative splicing; glutamate-cysteine ligase regulatory protein; Glutamate--cysteine ligase regulatory subunit; glutamate-cysteine ligase, modifier subunit; GSC light chain; null