This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
JAK1 Recombinant Rabbit Monoclonal Antibody (JM75-03)
catalog :
MA5-32780
quantity :
100 uL
price :
US 474.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
JM75-03

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
JAK1 Recombinant Rabbit Monoclonal Antibody (JM75-03)
Catalog # :
MA5-32780
Quantity :
100 uL
Price :
US 474.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200-1:2,000, Western Blot: 1:500-1:1,000
Species :
Human, Mouse, Rat
Clone :
JM75-03
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha/beta and -gamma signal transduction pathways. Immunological stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK1. JAK1 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription. Upon ligand binding, JAK1 undergoes tyrosine phosphorylation and catalytic activation in an interdependent manner. Phosphorylation of tyrosine residues at positions 1022 and 1023 is believed to function in the activation of catalytic events.
Immunogen :
Synthetic peptide within Human JAK1 aa 621-670
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200-1:2,000, Western Blot: 1:500-1:1,000
Aliases :
AA960307; BAP004; C130039L05Rik; EC 2.7.10.2; Jak1; JAK-1; JAK1A; JAK1B; Janus kinase 1; Janus protein tyrosine kinase 1; JTK3; kinase Jak1; Tyrosine-protein kinase JAK1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA