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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ADAM10 Recombinant Rabbit Monoclonal Antibody (JM32-11)
catalog :
MA5-32616
quantity :
100 uL
price :
US 474.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
JM32-11
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
more info or order :
Invitrogen product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 6c
Xu B, He Y, Liu L, Ye G, Chen L, Wang Q, et al. The Effects of Physical Running on Dendritic Spines and Amyloid-beta Pathology in 3xTg-AD Male Mice. Aging Dis. 2022;13:1293-1310 pubmed publisher
product information
Product Type :
Antibody
Product Name :
ADAM10 Recombinant Rabbit Monoclonal Antibody (JM32-11)
Catalog # :
MA5-32616
Quantity :
100 uL
Price :
US 474.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunoprecipitation: 1-2 ug/sample, Western Blot: 1:1,000-1:2,000
Species :
Human, Mouse, Rat
Clone :
JM32-11
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Proinflammatory cytokine tumor necrosis factor-a (TNF-a) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta (1-3). The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.
Immunogen :
Synthetic peptide within Human ADAM10 aa 715-748
Format :
Liquid
Applications w/Dilutions :
Immunoprecipitation: 1-2 ug/sample, Western Blot: 1:1,000-1:2,000
Aliases :
1700031C13Rik; a disintegrin and metallopeptidase domain 10; a disintegrin and metalloprotease domain (ADAM) 10; a disintegrin and metalloprotease domain 10; a disintegrin and metalloproteinase; AD10; AD18; ADAM; ADAM 10; ADAM metallopeptidase domain 10; ADAM10; ADAMs; CD156c; CDw156; Disintegrin and metalloproteinase domain-containing protein 10; HsT18717; KUZ; kuzbanian; kuzbanian protein homolog; MADM; Mammalian disintegrin-metalloprotease; metalloendopeptidases; metalloproteinase; myelin-associated metalloproteinase; RAK
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA