This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD71 (Transferrin Receptor) Recombinant Rabbit Monoclonal Antibody (JF0956)
catalog :
MA5-32500
quantity :
100 uL
price :
US 464.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
JF0956
reactivity :
human, mouse, rat
application :
western blot, flow cytometry
citations: 1
Reference
Arumov A, Liyanage P, Trabolsi A, Roberts E, Li L, Ferreira B, et al. Optimized Doxorubicin Chemotherapy for Diffuse Large B-cell Lymphoma Exploits Nanocarrier Delivery to Transferrin Receptors. Cancer Res. 2021;81:763-775 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD71 (Transferrin Receptor) Recombinant Rabbit Monoclonal Antibody (JF0956)
Catalog # :
MA5-32500
Quantity :
100 uL
Price :
US 464.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: 1:50-1:100, Western Blot: 1:1,000-1:5,000
Species :
Human, Mouse, Rat
Clone :
JF0956
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
Immunogen :
Synthetic peptide within Human CD71 aa 22-60
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50-1:100, Western Blot: 1:1,000-1:5,000
Aliases :
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA