This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MKP-1 Recombinant Rabbit Monoclonal Antibody (JJ0930)
catalog :
MA5-32480
quantity :
100 uL
price :
US 464.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
JJ0930

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 2
Reference
Yan Q, Xun Y, Lei D, Zhai H. Tanshinone IIA protects motor neuron-like NSC-34 cells against lipopolysaccharide-induced cell injury by the regulation of the lncRNA TCTN2/miR-125a-5p/DUSP1 axis. Regen Ther. 2023;24:417-425 pubmed publisher
Zhao W, Wang Q. Knockdown of TRIM9 attenuates irinotecan‑induced intestinal mucositis in IEC‑6 cells by regulating DUSP6 expression via the P38 pathway. Mol Med Rep. 2021;24: pubmed publisher
product information
Product Type :
Antibody
Product Name :
MKP-1 Recombinant Rabbit Monoclonal Antibody (JJ0930)
Catalog # :
MA5-32480
Quantity :
100 uL
Price :
US 464.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: 1:1,000, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:500-1:2,000
Species :
Human, Mouse, Rat
Clone :
JJ0930
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.
Immunogen :
Synthetic peptide within Human DUSP1 aa 112-156
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:1,000, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:500-1:2,000
Aliases :
3ch134; 3CH134/CL100 PTPase; CL 100; CL100; dual specificity phosphatase 1; dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; DUS1; DUSP1; EC 3.1.3.16; EC 3.1.3.48; erp; HVH1; MAP kinase phosphatase 1; MAP kinase phosphatase-1; mitogen-activated protein (MAP) kinase phosphatase-1; mitogen-activated protein kinase phosphatase 1; mitogen-activated protein kinase phosphatase-1; MKP1; mkp-1; oxidative stress-inducible protein tyrosine phosphatase; protein tyrosine phosphatase non-receptor type 16; protein tyrosine phosphatase, non-receptor type 16; protein-tyrosine phosphatase 3CH134; Protein-tyrosine phosphatase CL100; protein-tyrosine phosphatase ERP; Protein-tyrosine phosphatase non-receptor type 16; PTPN10; Ptpn16; serine/threonine specific protein phosphatase; U19515; VH1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA