ZNRF2 Recombinant Rabbit Monoclonal Antibody (JJ0924) | Invitrogen MA5-32477 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZNRF2 Recombinant Rabbit Monoclonal Antibody (JJ0924)

catalog :

MA5-32477

quantity :

100 uL

price :

US 474.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

JJ0924

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

ZNRF2 Recombinant Rabbit Monoclonal Antibody (JJ0924)

Catalog # :

MA5-32477

Quantity :

100 uL

Price :

US 474.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:1,000-1:2,000

Species :

Human, Mouse, Rat

Clone :

JJ0924

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). ZNRF2 (zinc and ring finger 2), also known as RNF202, is a 242 amino acid peripheral membrane protein that contains one RING-type zinc finger and localizes to the lysosome, as well as the endosome and the cell junction. Expressed at high levels in brain tissue, ZNRF2 is thought to function as an E3 ubiquitin-protein ligase that may be involved in the establishment and maintenance of neuronal transmission and plasticity. Upon DNA damage, ZNRF2 is subject to phosphorylation, probably by ATR or ATM.

Immunogen :

Synthetic peptide within Human ZNRF2 aa 162-206

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:1,000-1:2,000

Aliases :

1190002C14Rik; AU044205; D6Ertd365e; E3 ubiquitin-protein ligase ZNRF2; protein Ells2; RING finger protein 202; RING-type E3 ubiquitin transferase ZNRF2; RNF202; zinc and ring finger 1; zinc and ring finger 2; zinc and ring finger 2, E3 ubiquitin protein ligase; zinc finger/RING finger 2; zinc/RING finger protein 2; Znrf1; Znrf2