CD31 (PECAM-1) Recombinant Rabbit Monoclonal Antibody (SU03-59) | Invitrogen MA5-32126 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD31 (PECAM-1) Recombinant Rabbit Monoclonal Antibody (SU03-59)

catalog :

MA5-32126

quantity :

100 uL

price :

US 464.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

SU03-59

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Al Ghadban S, Walczak S, Isern S, Martin E, Herbst K, Bunnell B. Enhanced Angiogenesis in HUVECs Preconditioned with Media from Adipocytes Differentiated from Lipedema Adipose Stem Cells In Vitro. Int J Mol Sci. 2023;24: pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD31 (PECAM-1) Recombinant Rabbit Monoclonal Antibody (SU03-59)

Catalog # :

MA5-32126

Quantity :

100 uL

Price :

US 464.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:50-1:1,000, Western Blot: 1:1,000-1:2,000

Species :

Human

Clone :

SU03-59

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Immunogen :

Synthetic peptide within Human CD31 aa 689-738

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:50-1:1,000, Western Blot: 1:1,000-1:2,000

Aliases :

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule