This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
N-cadherin Recombinant Rabbit Monoclonal Antibody (SY02-46)
catalog :
MA5-32088
quantity :
100 uL
price :
US 483.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
SY02-46
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 2
Reference
Chen W, Wang H, Ji J, WANG Z, Shi T, Wu M, et al. Epigenetic network of EZH2/SFRP1/Wnt in the epithelial-mesenchymal transition of laryngeal carcinoma cells. Neoplasma. 2022;69:680-690 pubmed publisher
Dadwal U, Bhatti F, Awosanya O, Nagaraj R, Perugini A, Sun S, et al. The effects of bone morphogenetic protein 2 and thrombopoietin treatment on angiogenic properties of endothelial cells derived from the lung and bone marrow of young and aged, male and female mice. FASEB J. 2021;35:e21840 pubmed publisher
product information
Product Type :
Antibody
Product Name :
N-cadherin Recombinant Rabbit Monoclonal Antibody (SY02-46)
Catalog # :
MA5-32088
Quantity :
100 uL
Price :
US 483.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Canine, Human, Mouse, Rat
Applications :
Immunohistochemistry (Paraffin): 1:10,000-1:14,000, Western Blot: 1:1,000-1:5,000
Species :
Canine, Human, Mouse, Rat
Clone :
SY02-46
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry.
Immunogen :
Synthetic peptide within Human N Cadherin aa 161-210
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:10,000-1:14,000, Western Blot: 1:1,000-1:5,000
Aliases :
bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1 preproprotein; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; CDH2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; neural cadherin; Neural cadherin A; neural cadherin-2; neural calcium-dependent cell adhesion molecule; neural-cadherin; pac; Parachute; unnamed protein product; wu:fb47h04; XELAEV_18031953mg; ZNCAD
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA