COL17A1 Recombinant Rabbit Monoclonal Antibody (SR46-05) | Invitrogen MA5-31984 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

COL17A1 Recombinant Rabbit Monoclonal Antibody (SR46-05)

catalog :

MA5-31984

quantity :

100 uL

price :

US 470.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

SR46-05

The same clone is also sold as:

Novus Biologicals: NBP2-67316

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Ghuwalewala S, Lee S, Jiang K, Baidya J, Chovatiya G, Kaur P, et al. Binary organization of epidermal basal domains highlights robustness to environmental exposure. EMBO J. 2022;41:e110488 pubmed publisher

product information

Product Type :

Antibody

Product Name :

COL17A1 Recombinant Rabbit Monoclonal Antibody (SR46-05)

Catalog # :

MA5-31984

Quantity :

100 uL

Price :

US 470.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:50, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse, Rat

Clone :

SR46-05

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

COL17A1 is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein, and a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. COL17A1 is a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Moreover, COL17A1 is localized to tissues containing type I collagen so, like other members of this collagen family, it may serve to maintain the integrity of the extracellular matrix. Diseases associated with COL17A1 dysfunction include epithelial recurrent erosion dystrophy and epidermolysis bullosa.

Immunogen :

Recombinant protein within Human Collagen XVII aa 1313-1420

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:1,000-1:5,000

Aliases :

120 kDa linear IgA dermatosis antigen; 120 kDa linear IgA disease antigen; 120 kDa linear IgA disease antigen homolog; 180 kDa bullous pemphigoid antigen 2; 97 kDa LAD antigen; 97 kDa linear IgA bullous dermatosis antigen; 97 kDa linear IgA disease antigen; alpha 1 type XVII collagen; BA16H23.2; bA16H23.2 (collagen, type XVII, alpha 1 (BP180)); BP180; BPA-2; Bpag; BPAG2; Bullous pemphigoid antigen 2; bullous pemphigoid antigen 2 (180kD); Col17a1; Collagen alpha-1(XVII) chain; collagen type XVII alpha 1; collagen XVII, alpha-1 polypeptide; collagen, type XVII, alpha 1; ERED; LABD97; LAD-1; Linear IgA bullous disease antigen of 97 kDa; Linear IgA disease antigen 1; procollagen, type XVII, alpha 1; type XVII collagen alpha-1