product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
LRP1 Recombinant Rabbit Monoclonal Antibody (SA0290)
catalog :
MA5-31959
quantity :
100 uL
price :
US 530.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
SA0290
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Invitrogen product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:300; loading ...
He B, Chen P, Zambrano S, Dabaghie D, Hu Y, Möller Hackbarth K, et al. Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes. Nat Commun. 2021;12:2141 pubmed publisher
Shi X, Wang Z, Ren W, Chen L, Xu C, Li M, et al. LDL receptor-related protein 1 (LRP1), a novel target for opening the blood-labyrinth barrier (BLB). Signal Transduct Target Ther. 2022;7:175 pubmed publisher
Shimizu Albergine M, Basu D, Kanter J, Kramer F, Kothari V, Barnhart S, et al. CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins. J Clin Invest. 2021;131: pubmed publisher
product information
Product Type :
Antibody
Product Name :
LRP1 Recombinant Rabbit Monoclonal Antibody (SA0290)
Catalog # :
MA5-31959
Quantity :
100 uL
Price :
US 530.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 1:50, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:200-1:2,000, Immunoprecipitation: 1-2 ug/sample, Western Blot: 1:1000-1:5,000
Species :
Human, Mouse, Rat
Clone :
SA0290
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.
Immunogen :
Synthetic peptide within Human LRP1 aa 4,471-4,520
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:50, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:200-1:2,000, Immunoprecipitation: 1-2 ug/sample, Western Blot: 1:1000-1:5,000
Aliases :
A2MR; AI316852; alpha 2-macroglobulin receptor; alpha-2-macroglobulin receptor; APOER; Apolipoprotein E receptor; APR; b2b1554Clo; CD91; FLJ16451; IGFBP3R; LDL receptor related protein 1; lipoprotein receptor-related protein; low density lipoprotein receptor-related protein 1; low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor); Low-density lipoprotein receptor-related protein 1 515 kDa subunit; Low-density lipoprotein receptor-related protein 1 85 kDa subunit; Low-density lipoprotein receptor-related protein 1 intracellular domain; Lrp; Lrp1; LRP-1; LRP1A; LRP-515; LRP-85; LRPICD; MGC88725; Prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; TGFBR5; type V tgf-beta receptor
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA