RAD52 Monoclonal Antibody (5E11E7) | Invitrogen MA5-31888 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RAD52 Monoclonal Antibody (5E11E7)

catalog :

MA5-31888

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5E11E7

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:500; loading ...; fig 5c	Bloniarz D, Adamczyk Grochala J, Lewinska A, Wnuk M. The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence. Aging (Albany NY). 2021;13:15833-15874 pubmed publisher
	Hu X, Biswas A, De S. KMT2C-deficient tumors have elevated APOBEC mutagenesis and genomic instability in multiple cancers. NAR Cancer. 2022;4:zcac023 pubmed publisher
	Dibitetto D, Sims J, Ascenção C, Feng K, Kim D, Oberly S, et al. Intrinsic ATR signaling shapes DNA end resection and suppresses toxic DNA-PKcs signaling. NAR Cancer. 2020;2:zcaa006 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RAD52 Monoclonal Antibody (5E11E7)

Catalog # :

MA5-31888

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human

Clone :

5E11E7

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which includeRAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.

Immunogen :

Purified recombinant fragment of human RAD52 (AA: 269-418) expressed in E. coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

DNA repair protein RAD52 homolog; RAD52; RAD52 homolog (S. cerevisiae); RAD52 homolog, DNA repair protein; Rad52yh; recombination protein RAD52; rhabdomyosarcoma antigen MU-RMS-40.23

more info or order :

Invitrogen product webpage