ATF3 Monoclonal Antibody (CL1685) | Invitrogen MA5-31360 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ATF3 Monoclonal Antibody (CL1685)

catalog :

MA5-31360

quantity :

100 uL

price :

US 514.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CL1685

The same clone is also sold as:

Novus Biologicals: NBP2-34489
Abcam: ab191513

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Lu X, Zhong L, Lindell E, Veanes M, Guo J, Zhao M, et al. Identification of ATF3 as a novel protective signature of quiescent colorectal tumor cells. Cell Death Dis. 2023;14:676 pubmed publisher
S xe6 terstad S, xd8 stvik A, R xf8 yset E, Bakke I, Sandvik A, Granlund A. Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn's disease. PLoS ONE. 2022;17:e0265189 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ATF3 Monoclonal Antibody (CL1685)

Catalog # :

MA5-31360

Quantity :

100 uL

Price :

US 514.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 2-10 ug/ml, Immunohistochemistry (Paraffin): 1:20-1:50

Species :

Human

Clone :

CL1685

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

ATF3 (Activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene.

Immunogen :

Recombinant protein corresponding to Human ATF3

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2-10 ug/ml, Immunohistochemistry (Paraffin): 1:20-1:50

Aliases :

activating transcription factor 3; ATF 3; ATF3; cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3; Liver regeneration factor 1; Lrf1; LRF-1; LRFI; LRG-21; MGC137608 protein; transcription factor LRG-21; zgc:55526