This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MCPT-1 Recombinant Rabbit Monoclonal Antibody (43)
catalog :
MA5-31052
quantity :
100 uL
price :
US 414.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
43

The same clone is also sold as:
reactivity :
mouse
product information
Product Type :
Antibody
Product Name :
MCPT-1 Recombinant Rabbit Monoclonal Antibody (43)
Catalog # :
MA5-31052
Quantity :
100 uL
Price :
US 414.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Mouse
Applications :
ELISA: 1:5,000-1:10,000
Species :
Mouse
Clone :
43
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
MCPT-1 is the only chymase expressed by intestinal mucosal mast cells, which are found in the intestinal epithelium. Although it is expressed constitutively and is detectable in the sera of normal mice, parasites in the gut cause systemic levels to increase dramatically within two days and peak at two weeks following infection. It plays an important role in host defense against intestinal parasites, as mice deficient in MCPT-1 display delayed response upon infection. Elevated MCPT-1 levels are also observed during intestinal allergic hypersensitivity reactions. The mechanism of its action is not fully understood, although it is believed to increase intestinal permeability similarly to rMCPT-II, possibly by cleaving the proteins at tight junctions between cells.
Immunogen :
Recombinant Mouse MCPT1 protein (Met1-Lys246)
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:5,000-1:10,000
Aliases :
AV080368; mast cell protease 1; Mcp-1; Mcpt1; mMCP-1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA