This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
AMICA Monoclonal Antibody (06)
catalog :
MA5-30943
quantity :
100 uL
price :
US 323.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6
reactivity :
human
product information
Product Type :
Antibody
Product Name :
AMICA Monoclonal Antibody (06)
Catalog # :
MA5-30943
Quantity :
100 uL
Price :
US 323.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: 1:1,000-1:10,000
Species :
Human
Clone :
6
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
AMICA transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.
Immunogen :
Recombinant Human JAML/AMICA1 Protein (Met1-Leu275)
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:1,000-1:10,000
Aliases :
adhesion molecule AMICA; adhesion molecule interacting with CXADR antigen 1; adhesion molecule, interacts with CXADR antigen 1; AMICA; Amica1; Crea7; CREA7-1; CREA7-4; Dendritic cell-specific protein CREA7; Dendritic cell-specific protein CREA7-1; dendritic-cell specific protein Crea7; dendritic-cell specific protein CREA7-1; dendritic-cell specific protein CREA7-4; Gm638; Jaml; junction adhesion molecule like; junctional adhesion molecule-like; mCrea7; UNQ722/PRO1387
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA