This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NRG3 Monoclonal Antibody (06)
catalog :
MA5-30716
quantity :
100 uL
price :
US 323.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6
reactivity :
human
product information
Product Type :
Antibody
Product Name :
NRG3 Monoclonal Antibody (06)
Catalog # :
MA5-30716
Quantity :
100 uL
Price :
US 323.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: 1:1,000-1:2,000
Species :
Human
Clone :
6
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3. NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.
Immunogen :
Recombinant Human NRG-3/Neuregulin-3 Protein (Glu282-Pro342)
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:1,000-1:2,000
Aliases :
HGNC:7999; HRG3; neuregulin 3; neuregulin 3 variant 1; neuregulin 3 variant 10; neuregulin 3 variant 11; neuregulin 3 variant 12; neuregulin 3 variant 13; neuregulin 3 variant 14; neuregulin 3 variant 3; neuregulin 3 variant 4; neuregulin 3 variant 5; neuregulin 3 variant 6; neuregulin 3 variant 7; neuregulin 3 variant 8; neuregulin 3 variant 9; Neuregulin-3; neuregulin-3-like polypeptide; NRG3; NRG-3; Pro-neuregulin-3, membrane-bound isoform; pro-NRG3; RGD1559678; scaramanga; ska
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA