VEGF Receptor 3 Monoclonal Antibody (2B2F12C5) | Invitrogen MA5-30603 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

VEGF Receptor 3 Monoclonal Antibody (2B2F12C5)

catalog :

MA5-30603

quantity :

100 uL

price :

US 323.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B2F12C5

The same clone is also sold as:

Sino Biological: 10806-MM03

reactivity :

human

product information

Product Type :

Antibody

Product Name :

VEGF Receptor 3 Monoclonal Antibody (2B2F12C5)

Catalog # :

MA5-30603

Quantity :

100 uL

Price :

US 323.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:1,000-1:2,000

Species :

Human

Clone :

2B2F12C5

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.

Immunogen :

Recombinant Human VEGFR3 protein (Met1-Ile776)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:1,000-1:2,000

Aliases :

AI323512; Chy; chylous ascites; Flt4; FLT-4; FLT41; fms related tyrosine kinase 4; FMS-like tyrosine kinase 4; fms-related tyrosine kinase 4; LMPH1A; PCL; receptor protein tyrosine kinase; soluble VEGFR 3; sVEGFR 3; tyrosine-protein kinase receptor FLT4; Vascular endothelial growth factor receptor 3; vascular endothelial growth factor receptor-3; VEGF R3; VEGFR3; VEGFR-3