SIRT1 Monoclonal Antibody (3H10A10) | Invitrogen MA5-29570 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SIRT1 Monoclonal Antibody (3H10A10)

catalog :

MA5-29570

quantity :

100 uL

price :

US 323.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3H10A10

The same clone is also sold as:

Sino Biological: 11748-MM04

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

SIRT1 Monoclonal Antibody (3H10A10)

Catalog # :

MA5-29570

Quantity :

100 uL

Price :

US 323.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:1,000-1:2,000, Immunocytochemistry: 1:20-1:100, Immunohistochemistry (Paraffin): 1:500-1:2,000

Species :

Human

Clone :

3H10A10

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

NAD-dependent protein deacetylase sirtuin-1 (SIRT1) links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, repsonse to DNA damage, metabolism, apoptosis, and autophagy. SIRT1 can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histone and DNA, leading to transcriptional repression. It is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).

Immunogen :

Recombinant Human SIRT1 protein (Met193-Ser747)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:1,000-1:2,000, Immunocytochemistry: 1:20-1:100, Immunohistochemistry (Paraffin): 1:500-1:2,000

Aliases :

75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1