This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GSTM2 Recombinant Rabbit Monoclonal Antibody (005)
catalog :
MA5-29311
quantity :
100 uL
price :
US 414.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
5
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Zhang W, Shi Y, Niu S, Li L, Lin L, Gao X, et al. Integrated computer analysis and a self-built Chinese cohort study identified GSTM2 as one survival-relevant gene in human colon cancer potentially regulating immune microenvironment. Front Oncol. 2022;12:881906 pubmed publisher
product information
Product Type :
Antibody
Product Name :
GSTM2 Recombinant Rabbit Monoclonal Antibody (005)
Catalog # :
MA5-29311
Quantity :
100 uL
Price :
US 414.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1:100-1:500
Species :
Human
Clone :
5
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM2 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
Immunogen :
Recombinant Human GSTM2 protein (Met1-Lys218)
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:100-1:500
Aliases :
glutathione S-alkyltransferase M2; glutathione S-aralkyltransferase M2; glutathione S-aryltransferase M2; glutathione S-transferase 4; glutathione S-transferase M1; glutathione S-transferase M2; glutathione S-transferase M2 (muscle); glutathione S-transferase Mu 2; glutathione S-transferase mu 2 (muscle); glutathione S-transferase pmGT2; Glutathione S-transferase Yb-2; glutathione S-transferase Yb2 subunit; glutathione S-transferase, mu 2; Glutathione-S-transferase mu type 2 (Yb2); glutathione-S-transferase, mu 2; Glutathione-S-transferase, mu type 2 (Yb2); GST 4-4; GST 5-5; GST class-mu 2; GST Yb2; GST, muscle; GST4; GSTA4; Gstb2; Gstb-2; GSTM; GSTM2; GSTM2-2; GTHMUS; MGC117303; S-(hydroxyalkyl)glutathione lyase M2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA