N-cadherin Recombinant Rabbit Monoclonal Antibody (014) | Invitrogen MA5-29138 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

N-cadherin Recombinant Rabbit Monoclonal Antibody (014)

catalog :

MA5-29138

quantity :

100 uL

price :

US 422.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

reactivity :

human

citations: 1

Reference
Hohmann U, von Widdern J, Ghadban C, Giudice M, Lemahieu G, Cavalcanti Adam E, et al. Jamming Transitions in Astrocytes and Glioblastoma Are Induced by Cell Density and Tension. Cells. 2022;12: pubmed publisher

product information

Product Type :

Antibody

Product Name :

N-cadherin Recombinant Rabbit Monoclonal Antibody (014)

Catalog # :

MA5-29138

Quantity :

100 uL

Price :

US 422.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 1:5,000-1:10,000

Species :

Human

Clone :

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry.

Immunogen :

Recombinant Human N-Cadherin/CD325/CDH2 protein (Met1-Ala724)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:5,000-1:10,000

Aliases :

bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1 preproprotein; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; CDH2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; neural cadherin; Neural cadherin A; neural cadherin-2; neural calcium-dependent cell adhesion molecule; neural-cadherin; pac; Parachute; unnamed protein product; wu:fb47h04; XELAEV_18031953mg; ZNCAD