CD83 Recombinant Rabbit Monoclonal Antibody (104) | Invitrogen MA5-29132 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD83 Recombinant Rabbit Monoclonal Antibody (104)

catalog :

MA5-29132

quantity :

100 µL

price :

US 414

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

104

reactivity :

human, mouse

application :

western blot, flow cytometry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 4d	Lee Y, Kim T, Kim Y, Kim S, Lee S, Seo S, et al. Microbiota-derived lactate promotes hematopoiesis and erythropoiesis by inducing stem cell factor production from leptin receptor+ niche cells. Exp Mol Med. 2021;53:1319-1331 pubmed publisher
flow cytometry; mouse; loading ...; fig 3c	Sivasubramaniyam T, Yang J, Cheng H, Zyla A, Li A, Besla R, et al. Dj1 deficiency protects against atherosclerosis with anti-inflammatory response in macrophages. Sci Rep. 2021;11:4723 pubmed publisher
flow cytometry; mouse; 1:200; loading ...; fig 5a	Yao C, Lou G, Sun H, Zhu Z, Sun Y, Chen Z, et al. BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells. Nat Immunol. 2021;22:370-380 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD83 Recombinant Rabbit Monoclonal Antibody (104)

Catalog # :

MA5-29132

Quantity :

100 µL

Price :

US 414

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 1:500-1:2,000

Species :

Human

Clone :

104

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

CD83 cell surface antigen is a 40-45kD glycoprotein expressed by peripheral blood dendritic cells. Peripheral lymphocytes can be induced to express very low levels of CD83 after culture in agents such as Con A or PHA. In immunohistology, CD83 is shown to be expressed strongly by interfollicular interdigitating reticulum cells and more weakly by cells within germinal centres. CD83 is also expressed by Langerhan's cells in the skin. The CD83 antigen is a 186-amino-acid single-chain glycoprotein and this molecule is a member of the immunoglobulin superfamily that is composed of an extracellular V-type Ig-like single domain, a transmembrane region, and a short, 40-amino-acid cytoplasmic tail. CD83 antigen undergoes extensive post-translational glycosylation, since the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immuno-phenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also co-express T cell markers (CD2, CD5), B cell markers (CD40, CD78), myeloid cell markers (CD13, CD33, CD36), cytokine receptors as well as other cell surface molecules. Diseases associated with CD83 dysfunction include plague and Rift Valley Fever.

Immunogen :

Recombinant Human CD83 Protein (Met1-Ala143)

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500-1:2,000

Aliases :

B-cell activation protein; BL11; CD antigen CD83; CD83; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; cell surface protein HB15; cell-surface glycoprotein; HB15; hCD83; mCD83

more info or order :

Invitrogen product webpage