product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD53 Recombinant Rabbit Monoclonal Antibody (104)
catalog :
MA5-28983
quantity :
100 µL
price :
US 389.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
104
reactivity :
crab eating macaque, mouse
application :
western blot, ELISA, immunoprecipitation, flow cytometry
more info or order :
Invitrogen product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 4d
Lee Y, Kim T, Kim Y, Kim S, Lee S, Seo S, et al. Microbiota-derived lactate promotes hematopoiesis and erythropoiesis by inducing stem cell factor production from leptin receptor+ niche cells. Exp Mol Med. 2021;53:1319-1331 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3c
Sivasubramaniyam T, Yang J, Cheng H, Zyla A, Li A, Besla R, et al. Dj1 deficiency protects against atherosclerosis with anti-inflammatory response in macrophages. Sci Rep. 2021;11:4723 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 5a
Yao C, Lou G, Sun H, Zhu Z, Sun Y, Chen Z, et al. BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells. Nat Immunol. 2021;22:370-380 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD53 Recombinant Rabbit Monoclonal Antibody (104)
Catalog # :
MA5-28983
Quantity :
100 µL
Price :
US 389.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Cynomolgus Monkey
Applications :
ELISA: 1:5,000-1:10,000, Immunoprecipitation: 1-4 µL/mg of lysate, Western Blot: 1:500-1:2,000
Species :
Cynomolgus Monkey
Clone :
104
Isotype :
IgG
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumor cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.
Immunogen :
Recombinant Cynomolgus CD53 Protein
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:5,000-1:10,000, Immunoprecipitation: 1-4 µL/mg of lysate, Western Blot: 1:500-1:2,000
Aliases :
AI323659; antigen MOX44 identified by monoclonal antibody MRC-OX44; Cd53; CD53 antigen; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; cell surface antigen; cell surface glycoprotein CD53; Leukocyte antigen MRC OX-44; leukocyte surface antigen CD53; MOX44; OX44; Ox-44; tetraspanin-25; transmembrane glycoprotein; TSPAN25; tspan-25
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA