This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD28 Monoclonal Antibody (37.51), PE-Cyanine5
catalog :
MA5-28655
quantity :
1 mL
price :
US 381.00
clonality :
monoclonal
host :
Syrian golden hamster
conjugate :
PE-Cy5
clone name :
37.51

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
product information
Product Type :
Antibody
Product Name :
CD28 Monoclonal Antibody (37.51), PE-Cyanine5
Catalog # :
MA5-28655
Quantity :
1 mL
Price :
US 381.00
Clonality :
Monoclonal
Purity :
purified
Host :
Syrian Hamster
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.2 ug/10^6 cells
Species :
Mouse
Clone :
37.51
Isotype :
IgG2
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes. Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells. In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR. The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells. Diseases associated with CD28 dysfunction include mycosis fungiodes and Sezary's Disease.
Immunogen :
C57BL/6N mouse T cell lymphoma EL-4 cell line
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.2 ug/10^6 cells
Aliases :
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA