This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SCIMP Monoclonal Antibody (NVL-07)
catalog :
MA5-28633
quantity :
100 ug
price :
US 241.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
NVL-07

The same clone is also sold as:
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
product information
Product Type :
Antibody
Product Name :
SCIMP Monoclonal Antibody (NVL-07)
Catalog # :
MA5-28633
Quantity :
100 ug
Price :
US 241.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1-2 ug/mL
Species :
Human
Clone :
NVL-07
Isotype :
IgG2a
Storage :
4 C, do not freeze
Description :
SCIMP (SLP adaptor and Csk interacting membrane protein), also known as Nvl, is a palmitoylated transmembrane adaptor protein expressed in professional antigen presenting cells, most prominently in the lymph nodes and spleen. It is associated with tetraspanin-enriched microdomains (together with MHC II). There is a close relationship between SCIMP and tyrosinkinase Lyn, which is constitutively bound to it by its SH3 domain. After MHC II-mediated stimulation in the immunological synapse SCIMP becomes phosphorylated at several tyrosine residues and provides docking sites for Grb2 and SLP65 or SLP76 adaptors transducing the signal downstream, as well as for the kinase Csk with modulatory roles.
Immunogen :
Human SCIMP (intracellular region)
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1-2 ug/mL
Aliases :
A430084P05Rik; C17orf87; DTFT5783; SCIMP; SLP adapter and CSK-interacting membrane protein; SLP adaptor and CSK interacting membrane protein; SLP65/SLP76, Csk-interacting membrane protein; transmembrane protein C17orf87; transmembrane protein C17orf87 homolog; UNQ5783; UNQ5783/PRO16090
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA